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What is Bilirubin Direct?

A Bilirubin Direct test measures the direct (conjugated) bilirubin in the blood. This test is suggested if your doctor suspects a liver disorder, such as jaundice, gallstones, hepatitis, etc. It may also be done as a routine health checkup or as part of a liver function test to monitor liver health.

What does Bilirubin Direct measure?

A Bilirubin Direct test measures the amount of direct or conjugated bilirubin present in your body. Bilirubin is a yellowish byproduct primarily produced when the body breaks down aged RBCs. When the RBCs finish their lifespan of 120 days, they break down and pass to the liver. In the liver, direct bilirubin–a form of bilirubin conjugated with glucuronic acid (sugar)–is processed, mixed with bile, and then excreted in the bile ducts and stored in your gallbladder. Finally, the bile is released into the small intestine where it is further broken down and helps digest fat. It is eventually excreted within your stool as a waste product.

Elevated levels of bilirubin can be indicative of various liver or bile duct issues. Additionally, higher bilirubin levels might result from an increased breakdown of red blood cells in the body.