Interactions / Warnings:
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy interaction:
Genxtor 25mg Injection may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Expert advice:
You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin. Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness. Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus. Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped. Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection. Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus. Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
Side Effects:
Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Low blood platelets, Increased heart rate, Decreased white blood cell count, Anemia (low number of red blood cells), Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.
How to use:
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How it works:
Genxtor 25mg Injection suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
Faq for medicine:
Q: Is Genxtor dialyzable?
A: Genxtor is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Q: Is Genxtor a calcineurin inhibitor?
A: Genxtor is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Q: Is Genxtor cytotoxic?
A: Genxtor is a cytotoxic agent
Q: What is Genxtor-eluting stent?
A: The Genxtor-eluting stent is a metal stent coated with 140 µg/cm2 of Genxtor blended with synthetic polymers. After stent implantation, Genxtor is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Q: Does Genxtor cause hair loss?
A: Genxtor causes hair loss
Q: Why does Genxtor cause hyperlipidemia?
A: Genxtor alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
Medicine interaction:
Genxtor with Roxithromycin|Genxtor with Clarithromycin|Genxtor with Varicella Vaccine (live) attenuated|Genxtor with Azithromycin|Genxtor with Bacillus Calmette-Guerin high strength|Genxtor with Bacillus Calmette-Guerin|Genxtor with Rotavirus vaccine (live attenuated,oral)|Genxtor with Rubella vaccine (Live)|Genxtor with Voriconazole|Genxtor with Erythromycin|Genxtor with Spiramycin|Genxtor with Inactivated Japanese Encephalitis virus protein|Genxtor with Rifampicin|Genxtor with Posaconazole|Genxtor with Phenytoin|Genxtor with Benidipine|Genxtor with Ritonavir|Genxtor with S-Amlodipine|Genxtor with Danazol|Genxtor with Ramipril|Genxtor with Lercanidipine|Genxtor with Fosphenytoin|Genxtor with Nimodipine|Genxtor with Cilnidipine|Genxtor with Itraconazole|Genxtor with Nifedipine|Genxtor with Carbamazepine|Genxtor with Enalapril|Genxtor with Perindopril|Genxtor with Amlodipine|Genxtor with Fluconazole|Genxtor with Ketoconazole