Logit 15mg Tablet
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Manufactured By Khandelwal Laboratories Pvt Ltd
Composition Pioglitazone (15mg)
Package Size ( 10 Tablet in a strip )
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MRP Rs 19.50
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Interactions / Warnings:
Taking pioglitazone with alcohol may affect blood glucose levels in patients with diabetes.
Pregnancy interaction:
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Side Effects:
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Faq for medicine:
A: No. Logit is an anti-diabetic medication. Blood thinners are the medicine that prevents the formation of a harmful blood clot. These include medicines like Aspirin, Heparin and Warfarin.
Q: Is Logit a diuretic?
A: No. Logit is not a diuretic. It is used in the treatment of Diabetes Mellitus. Diuretics are those medicine which increases urination.
Q: Can Logit used in Hepatitis B infection?
A: Some studies have shown that Logit may be helpful in preventing Hepatitis B Virus-associated Hepatocellular Cancer (Liver Cancer). However, these findings are still very preliminary and clear role has not been established.
Q: Can Logit used in Hepatitis C infection?
A: Logit has been shown to inhibit Liver Cancer (HCC) recurrence in overweight Hepatitis C Virus-infected diabetic patients. It also improved insulin resistance (a state where the body is resistant to the effects and functions of the insulin hormone) in them.
Q: Can Logit used along with Vitamin D?
A: Studies indicate that Vitamin-D combined with Logit may be more effective in improving Bone Mineral Density and Bone Metabolism than Vitamin-D or Logit alone in the treatment of Diabetes Mellitus patients with kidney dysfunction (Diabetic Nephropathy).
Q: Can Logit be used along with sitagliptin?
A: Combination therapy with Sitagliptin and Logit leads to a substantial and sustained improvement in glycemic (blood sugar) control compared to the treatment with Logit alone. This is useful for patients who cannot tolerate Metformin or Sulfonylureas.
Q: Is there any role of Logit in Alzheimer disease?
A: Recent evidence suggests that Logit may be beneficial in Alzheimer's disease (AD), decreasing the cognitive decline early in the disease process. However, larger studies are now in progress to establish the same.
Q: Can Logit and repaglinide combined in diabetes treatment?
A: For patients who previously failed oral antidiabetic therapy, the combination of Repaglinide and Logit have acceptable safety, with greater reductions of glycemic parameters (blood sugar levels) than using either agent alone.
Q: Does Logit cause urinary bladder tumour?
A: Large population studies indicate that Logit is associated with an increased risk of bladder cancer. The absence of an association of bladder cancer with the other drug of the same class, Rosiglitazone, suggests that the increased risk is drug specific and not a class effect.
Q: Can Logit be used along with glimepiride in diabetes?
A: Logit when added to Glimepiride in Patients with Diabetes Mellitus, has been found to significantly reduce plasma lipid levels and significant improvement in blood pressure control related to a reduction in the insulin resistance.
Q: Is Logit a steroid?
A: No. Logit is not a steroid. It is an anti-diabetic medication which belongs to the class of thiazolidinediones.
Q: How to use Logit?
A: Logit is an anti-diabetes drug used along with a proper diet and exercise program to control high blood sugar in patients with type 2 diabetes. Logit acts as an insulin sensitizer and decreases the extent of insulin resistance in the body too.
Q: How safe is Logit?
A: Logit cardiovascular safety profile compares favourably with that of Rosiglitazone. Logit has been found to be associated with bladder tumours but causality assessment has not been proved yet.
Q: How does Logit cause oedema?
A: Logit increases the permeability of fluid in tiny blood vessels called capillaries. This results in easier movement of fluids across the membrane and their consequent accumulation, resulting in oedema (puffiness). Also, Logit causes increased sodium and water reabsorption from the kidney that contributes to the oedema.
Q: How does Logit cause bladder cancer?
A: The mechanism behind the link between Logit use and bladder cancer is still unknown. Studies have suggested that use of Logit for more than one year results in increased risk of development of tumour of the urinary bladder.
Q: How Logit protects against atherosclerosis?
A: Studies in animals have concluded that Logit improves the elasticity of the aortic wall ( the aorta is a large blood vessel that arises from the heart and supplies oxygenated blood to the rest of the body). This may be a mechanism by which it protects against atherosclerosis, but more studies are needed to confirm this.
Q: Can Logit be used with insulin?
A: The addition of Logit reduces daily insulin dosages, but study findings have not been consistent. Improvement of lipid profiles has also been weak with this combination therapy. Long-term studies are needed before any conclusions can be reached. Combination therapy should be primarily used for patients who achieve an insufficient reduction in blood sugar with insulin alone.
Q: Can Logit used for dementia?
A: Findings indicate that Logit treatment is associated with a reduced dementia risk in Diabetes mellitus patients. Prospective studies are needed to evaluate a possible neuroprotective effect in these patients in an ageing population.
Q: Can Logit used for infertility?
A: Logit may be of use in infertile patients with polycystic ovary syndrome (PCOS) who are resistant to conventional ovulation induction such as by drugs like Clomiphene, Dexamethasone, or Metformin.
Q: Can Logit used for psoriasis?
A: The use of Logit for plaque psoriasis treatment is controversial. Some studies revealed no effect of Logit 30 mg daily neither on the clinical response of moderate-to-severe psoriasis whereas others demonstrate that it could be considered as an efficacious and safe agent for the treatment of plaque psoriasis.
Q: Can Logit used for autism?
A: In a research study in a small number of autistic children, daily treatment with 30 or 60 mg Logit for 3–4 months induced apparent clinical improvement. Logit should be considered for further testing of therapeutic potential in autistic patients but as of now, autism is not an approved indication for Logit use.
Q: Can Logit be used in depression?
A: Logit, either alone or as add-on therapy to conventional treatments, could clinically benefit patients of major depression according to a study.
Q: Can Logit used for weight loss?
A: A recent study shows that although Logit causes a significant decrease in blood sugar, HbA1C and lipid levels, it is associated with weight gain, which would limit its utility. It has not been shown to cause weight loss.
Q: Can Logit be used to treat fatty liver?
A: Logit has also been used to treat non-alcoholic steatohepatitis (fatty liver), but this use is presently considered experimental.
Q: Can Logit be used for secondary stroke prevention?
A: Logit reduces recurrent stroke and major vascular events in stroke patients with insulin resistance, prediabetes, and diabetes mellitus. However, its use as a preventive therapy requires more research.
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