Q: Does Onglyza cause any weight loss (reduction)?
A: No, Onglyza neither causes weight loss nor weight gain. It is weight neutral. However, weight gain can be seen when Onglyza is used with other antidiabetic medicines like thiazolidinediones, sulfonylureas or insulin.

Q: Can Onglyza cause cancer?
A: Onglyza belongs to the group of drugs called incretins which have been associated with pancreatic cancer in some clinical studies. However, a definite evidence that they cause cancer is missing, so, it is advisable to talk to your doctor regarding the same.

Q: Can I use Onglyza with pioglitazone?
A: Yes, Onglyza can be used with pioglitazone. A combined use of the two medicines would be more effective in controlling blood sugar levels than either medicine alone. No drug-drug interactions or any change in side effect profile has been reported compared to when they are used alone.

Q: Is Onglyza useful in the treatment of parkinsonism?
A: Onglyza is seen to be efficacious in the management of parkinsonism in some animal research studies only and is not advised for the management of parkinsonism in humans currently.

Q: How beneficial is it to use a combination of Onglyza and gliclazide?
A: Yes, Onglyza and gliclazide can be taken together as they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase. Consult your doctor as a dose adjustment of the two may be needed.

Q: What is the benefit of using Onglyza with insulin?
A: Onglyza when taken with insulin can help in lowering the insulin dose and decrease the risk of hypoglycemia (low blood sugar levels). Consult your doctor as a dose adjustment of the two may be needed.

Q: Would the results be better if I take Onglyza with metformin?
A: Yes, metformin taken along with Onglyza can help in better reduction of blood sugar levels compared to either drug taken alone. Moreover, fixed dose combinations of Onglyza with metformin are available.

Q: Are there any contraindications to the use of Onglyza?
A: Yes, the use of Onglyza is contraindicated in some conditions like a history of allergy to Onglyza, any ingredients of this drug or to any other drug of the same class. Onglyza should also be avoided in patients with a history of pancreatitis.

Q: Can I use Onglyza with dapagliflozin?
A: Yes, Onglyza can be used along with dapagliflozin. Both are antidiabetic drugs and can achieve better reduction of blood sugar levels when used together and can lower the risk of hypoglycemia and help in better reduction of body weight.

Q: Is the use of Onglyza is associated with a high risk of heart failure?
A: Yes, there are some cases of Onglyza-induced heart failure reported especially in patients with additional risk factors for heart failure. In case the patient develops symptoms of heart failure like increasing shortness of breath, the rapid increase in weight and swelling of the feet (pedal edema). Stop taking Onglyza and inform your doctor.

Q: How effective is Onglyza for diabetes mellitus?
A: Onglyza is indicated along with dietary modification and exercise in adults with type 2 diabetes mellitus. It is seen to significantly reduce blood glucose levels and glycosylated hemoglobin (HbA1c) when taken as a single drug or in combination with other anti-diabetic drugs.

Q: Is it beneficial to use Onglyza with glipizide?
A: Yes, it is beneficial to take Onglyza and glipizide. Both are antidiabetic drugs, however, they work in different ways. When taken together, they can help in better control of blood sugar levels. However, the risk of low blood sugar levels (hypoglycemia) can increase if the dose of glipizide is not adjusted.