Pentanerv-NT Tablet is a combination medicine used for the treatment of neuropathic pain. This medicine decreases the pain by stopping the movement of pain signals to the brain.

Pentanerv-NT Tablet is taken by mouth, with or without food and preferably at night. It is advised to take it at a fixed time each day to maintain a consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Finish the full course of treatment even if you feel better. It is important not to stop taking this medicine suddenly without talking to the doctor as it may worsen your symptoms.

Some common side effects of this medicine constipation, difficulty in urination, weight gain, tiredness, and dryness in mouth. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. This medicine may cause weight gain and to control it, you should exercise regularly and take a balanced diet. Remember to inform the doctor if you develop any unusual changes in mood as this medicine may lead to suicidal thoughts.

Before taking this medicine let your doctor know if you suffer from kidney or liver disease. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

USES OF PENTANERV-NT TABLET

• Neuropathic pain

BENEFITS OF PENTANERV-NT TABLET

In Neuropathic pain

Pentanerv-NT Tablet is a combination medicine used to treat long-lasting (chronic) pain caused by nerve damage due to diabetes, shingles or spinal cord injury. It reduces pain and its associated symptoms such as mood changes, sleep problems, and tiredness. It is thought to work by interfering with pain signals that travel through the damaged nerves and the brain.
Using Pentanerv-NT Tablet regularly will improve your physical and social functioning and overall quality of life. It takes a few weeks to work so you need to use it regularly even if you feel it is not doing any good. Once your symptoms have gone you should still keep using the medicine until your doctor advises you to stop.

SIDE EFFECTS OF PENTANERV-NT TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Pentanerv-NT

• Constipation
• Difficulty in urination
• Weight gain
• Sleepiness
• Dizziness
• Tiredness
• Blurred vision
• Dryness in mouth
• Orthostatic hypotension (sudden lowering of blood pressure on standing)
• Increased heart rate
• Uncoordinated body movements

HOW TO USE PENTANERV-NT TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Pentanerv-NT Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW PENTANERV-NT TABLET WORKS

Pentanerv-NT Tablet is a combination of two medicines: Gabapentin and Nortriptyline. Gabapentin is an alpha 2 delta ligand which decreases the pain by modulating calcium channel activity of the nerve cells. Nortriptyline is a tricyclic antidepressant which increases the levels of chemical messengers (serotonin and noradrenaline) that stop the movement of pain signals in the brain. Together, they relieve neuropathic pain (pain from damaged nerves).

SAFETY ADVICE

Alcohol

UNSAFE

Pentanerv-NT Tablet may cause excessive drowsiness with alcohol.

Pregnancy

CONSULT YOUR DOCTOR

Pentanerv-NT Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breastfeeding

CONSULT YOUR DOCTOR

Pentanerv-NT Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

UNSAFE

Pentanerv-NT Tablet may cause side effects which could affect your ability to drive.
As Pentanerv-NT Tablet may affect your alertness which may affect your ability to drive.

Kidney

CAUTION

Pentanerv-NT Tablet should be used with caution in patients with kidney disease. Dose adjustment of Pentanerv-NT Tablet may be needed. Please consult your doctor.

Liver

CAUTION

Pentanerv-NT Tablet should be used with caution in patients with liver disease. Dose adjustment of Pentanerv-NT Tablet may be needed. Please consult your doctor.
Inform your doctor if you develop any signs and symptoms of jaundice while taking this medicine. Use of Pentanerv-NT Tablet is not recommended in patients with severe liver disease.