Interactions / Warnings:
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy interaction:
Raparen 1mg Injection may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Expert advice:
You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin. Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness. Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus. Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped. Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection. Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus. Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
Side Effects:
Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Low blood platelets, Increased heart rate, Decreased white blood cell count, Anemia (low number of red blood cells), Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.
How to use:
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How it works:
Raparen 1mg Injection suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
Faq for medicine:
Q: Is Raparen dialyzable?
A: Raparen is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Q: Is Raparen a calcineurin inhibitor?
A: Raparen is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Q: Is Raparen cytotoxic?
A: Raparen is a cytotoxic agent
Q: What is Raparen-eluting stent?
A: The Raparen-eluting stent is a metal stent coated with 140 µg/cm2 of Raparen blended with synthetic polymers. After stent implantation, Raparen is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Q: Does Raparen cause hair loss?
A: Raparen causes hair loss
Q: Why does Raparen cause hyperlipidemia?
A: Raparen alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
Medicine interaction:
Raparen with Varicella Vaccine (live) attenuated|Raparen with Bacillus Calmette-Guerin|Raparen with Inactivated Japanese Encephalitis virus protein|Raparen with Erythromycin|Raparen with Rotavirus vaccine (live attenuated,oral)|Raparen with Spiramycin|Raparen with Azithromycin|Raparen with Rubella vaccine (Live)|Raparen with Rifampicin|Raparen with Roxithromycin|Raparen with Bacillus Calmette-Guerin high strength|Raparen with Voriconazole|Raparen with Clarithromycin|Raparen with Nimodipine|Raparen with Phenytoin|Raparen with Amlodipine|Raparen with S-Amlodipine|Raparen with Cilnidipine|Raparen with Lercanidipine|Raparen with Benidipine|Raparen with Nifedipine|Raparen with Posaconazole|Raparen with Fluconazole|Raparen with Ketoconazole|Raparen with Fosphenytoin|Raparen with Danazol|Raparen with Enalapril|Raparen with Itraconazole|Raparen with Ramipril|Raparen with Ritonavir|Raparen with Perindopril|Raparen with Carbamazepine
Item requires a valid prescription
