Interactions / Warnings:
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy interaction:
Siropan 1mg Tablet may be unsafe to use during pregnancy.Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Expert advice:
You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin. Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness. Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus. Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped. Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection. Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus. Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
Side Effects:
Nausea, Headache, Abdominal pain, Viral infection, Pneumonia, Low blood platelets, Increased heart rate, Decreased white blood cell count, Anemia (low number of red blood cells), Urinary tract infection, Diarrhoea, Increased blood pressure, Bacterial infection, Fungal infection, Constipation, Herpes virus infection.
How to use:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siropan 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How it works:
Siropan 1mg Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
Faq for medicine:
Q: Is Siropan dialyzable?
A: Siropan is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Q: Is Siropan a calcineurin inhibitor?
A: Siropan is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Q: Is Siropan cytotoxic?
A: Siropan is a cytotoxic agent
Q: What is Siropan-eluting stent?
A: The Siropan-eluting stent is a metal stent coated with 140 µg/cm2 of Siropan blended with synthetic polymers. After stent implantation, Siropan is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Q: Does Siropan cause hair loss?
A: Siropan causes hair loss
Q: Why does Siropan cause hyperlipidemia?
A: Siropan alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.
Medicine interaction:
Siropan with Roxithromycin|Siropan with Clarithromycin|Siropan with Bacillus Calmette-Guerin high strength|Siropan with Bacillus Calmette-Guerin|Siropan with Azithromycin|Siropan with Rotavirus vaccine (live attenuated,oral)|Siropan with Rubella vaccine (Live)|Siropan with Voriconazole|Siropan with Inactivated Japanese Encephalitis virus protein|Siropan with Erythromycin|Siropan with Varicella Vaccine (live) attenuated|Siropan with Spiramycin|Siropan with Rifampicin|Siropan with Posaconazole|Siropan with Phenytoin|Siropan with Danazol|Siropan with Ritonavir|Siropan with Enalapril|Siropan with Fluconazole|Siropan with Benidipine|Siropan with Ramipril|Siropan with Lercanidipine|Siropan with Fosphenytoin|Siropan with Nimodipine|Siropan with Cilnidipine|Siropan with Itraconazole|Siropan with Nifedipine|Siropan with Carbamazepine|Siropan with Perindopril|Siropan with Amlodipine|Siropan with Ketoconazole|Siropan with S-Amlodipine
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